PRECISION MEDICINE USING WHOLE GENOME SEQUENCING IDENTIFIES A NOVEL DYSTROPHIN (DMD) VARIANT FOR X‐LINKED MUSCULAR DYSTROPHY IN A CAT

Precision medicine using whole genome sequencing identifies a novel dystrophin (DMD) variant for X‐linked muscular dystrophy in a cat

Abstract Background Muscular dystrophies (MDs) are a large, heterogeneous group of degenerative muscle diseases.X‐linked dystrophin‐deficient MD in cats is the first genetically characterized cat model for a human disease and a few novel forms have been identified.Hypothesis/Objectives Muscular dystrophy was suspected in a young male domestic s

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Combinational Optimization of the WRF Physical Parameterization Schemes to Improve Numerical Sea Breeze Prediction Using Micro-Genetic Algorithm

This study aims to improve the performance of the Weather Research and Forecasting (WRF) model in the sea breeze circulation using the micro-Genetic Algorithm (micro-GA).We found the optimal combination of four physical parameterization schemes related to the sea breeze system, including planetary boundary layer (PBL), land surface, shortwave radia

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